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'Optical Tweezers' Help in Quest for Better Cancer Treatments

A breakthrough in observing telomerase activity at a single-molecule level with unprecedented precision was recently achieved by Department of Physics and Astronomy assistant professor Matt Comstock and close collaborator assistant professor Jens Schmidt of the Department of Obstetrics, Gynecology and Reproductive Biology. Their results, published in a Nature Chemical Biology paper “Observation of processive telomerase catalysis using high-resolution optical tweezers”, utilized state of the art optical tweezers developed by the team to achieve their breakthrough in studying how telomerase works in real time.

See the related MSUToday article for a complete description of their work.