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Matthew Comstock

Associate Professor
Condensed Matter Physics - Experimental
Biomedical-Physical Sciences Bldg.
567 Wilson Rd., Room 4238
(517) 884-5645


B149 Biomedical-Physical Sciences Bldg.
(517) 884-5491
B238 Biomedical-Physical Sciences Bldg.
(517) 884-5705

2008: Ph.D., Physics, University of California, Berkeley;
2000: B.S., Physics, University of Chicago

Selected Publications

Direct observation of structure-function relationship in a nucleic acid–processing enzyme, M. J. Comstock,K. K. Whitley, H. Jia, J. Sokoloski, T. M. Lohman, Taekjip Ha, Y. R. Chemla, Science, 348, 352-354 [2015]

Ultrahigh-resolution optical trap with single-fluorophore sensitivity, Matthew J Comstock, Taekjip Ha, Yann R Chemla, Nature methods, 8 (4), 335-340 [2011]

Reversible photomechanical switching of individual engineered molecules at a metallic surface, Matthew J. Comstock, Niv Levy, et al., Physical Review Letters, 99 (3), 038301 [2007]

Professional Activities & Interests / Biographical Information

Dr. Comstock earned his undergraduate degree in physics from The University of Chicago and received a physics Ph.D. in condensed matter from the University of California, Berkeley, with research focused on optically controlled molecular machines. At the University of Illinois, Urbana-Champaign, Matt jumped into biological physics during a postdoctoral fellowship, where he constructed a novel microscope capable of observing in real-time both the structure and the function of individual biological molecular motors at the angstrom scale. In August 2012, Matt joined the faculty at MSU. As an assistant professor and the Jerry Cowen Chair of Physics, he will continue to advance the frontiers of single molecule biology experimental techniques.